How do we smell? – Rose Eveleth

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The lesson “How Do We Smell?” by Rose Eveleth explores the intricate process of the human sense of smell, highlighting its significance from birth and the genetic dedication to olfactory functions. It explains how odor molecules are detected by olfactory receptor cells in the nasal cavity, how signals are transmitted to the brain, and the unique features of olfactory neurons that differentiate individual smells. Additionally, the lesson addresses the phenomenon of anosmia, the impact of smell on taste, and encourages appreciation for this vital sense.

How Do We Smell? – Rose Eveleth

Did you know that your sense of smell is the first sense you use when you’re born? It’s so important that one out of every fifty of your genes is dedicated to it! Let’s explore how this amazing sense works.

The Journey of Smell

When you take a deep breath through your nose, you’re using your sense of smell. As an adult, you can recognize about 10,000 different smells! Here’s how your nose makes that happen.

Smelling begins when you breathe in molecules from the air through your nostrils. Most of your nasal cavity, about 95%, is used to filter the air before it reaches your lungs. But at the very back of your nose, there’s a special area called the olfactory epithelium. This small patch of tissue is crucial for detecting smells. It contains olfactory receptor cells, which are special neurons similar to taste buds.

How Smells Reach Your Brain

When odor molecules reach the back of your nose, they get trapped in a layer of mucus covering the olfactory epithelium. As they dissolve, they bind to the olfactory receptor cells. These cells then send signals through the olfactory tract to your brain. Interestingly, the size of an animal’s olfactory epithelium can tell you how good its sense of smell is. For example, dogs have a much larger olfactory epithelium than humans, which is why they can smell so well!

Understanding Different Smells

Even though we know a lot about how smell works, there are still mysteries. For instance, our olfactory epithelium is pigmented, and scientists are still figuring out why. So, how do you tell different smells apart? Your brain has about 40 million different olfactory receptor neurons, allowing for many combinations. For example, one smell might activate certain neurons, while another smell activates a different set. This variety helps you detect a wide range of smells.

Unique Features of Olfactory Neurons

Olfactory neurons are special because they are replaced every four to eight weeks. Once activated, the signals travel through a bundle called the olfactory tract to different parts of your brain, like the amygdala, thalamus, and neocortex. This process is different from how sight and sound are processed, as those signals first go to a relay center in the brain. Smell takes a more direct route, affecting your emotions, memories, and even appetite.

Why Smells Are Perceived Differently

Even though we all have the same basic setup, not everyone smells things the same way. For example, after eating asparagus, only about a quarter of people can detect a specific odor. Another example is the chemical androstenone, which some people think smells like vanilla, while others think it smells like sweat.

What Happens When You Can’t Smell

Not being able to smell a scent is called anosmia, and there are about 100 types of it. Some people can’t smell garlic or cloves, while others might have complete anosmia due to various reasons like congenital conditions, accidents, or illnesses. Swelling or infection of the olfactory epithelium can also affect your sense of smell, which is common when you’re sick.

When you can’t smell, it can affect your other senses too. Many people with anosmia have trouble tasting food because taste is closely linked to smell. When you chew, the aroma of your food travels up to your nasal passage, interacting with the olfactory epithelium and giving you more information about what you’re eating. Without the ability to smell, you might only notice the basic tastes: sweet, salty, bitter, sour, and savory.

Appreciating Your Sense of Smell

So, the next time you come across different scents, you’ll have a better understanding of how your sense of smell works. It’s an incredible ability that adds so much to your experiences, so take a moment to appreciate it!

  1. Reflect on a time when a particular smell triggered a strong memory or emotion for you. How does this experience relate to the article’s explanation of how smells affect emotions and memories?
  2. Considering the article’s information on the olfactory epithelium, how do you think the size of this area might influence your personal ability to detect different smells?
  3. The article mentions that olfactory neurons are replaced every four to eight weeks. How might this renewal process impact your perception of smells over time?
  4. Discuss a situation where you noticed a difference in smell perception compared to someone else. How does the article’s explanation of individual differences in smell perception help you understand this experience?
  5. How has your understanding of the connection between smell and taste changed after reading the article? Can you think of a personal experience where this connection was evident?
  6. Reflect on the concept of anosmia as described in the article. How might losing your sense of smell affect your daily life and interactions with the world?
  7. The article highlights the unique direct pathway of smell signals to the brain. How do you think this direct route influences the way smells impact your emotions and decisions?
  8. After learning about the complexity of the sense of smell, how might you approach or appreciate different scents in your environment differently?
  1. Smell Experiment

    Gather a variety of items with distinct scents, such as vanilla, lemon, coffee, and cinnamon. Close your eyes and have a friend hold each item under your nose one at a time. Try to identify each scent without looking. This will help you understand how your olfactory receptor cells work to recognize different smells.

  2. Olfactory Neurons Art Project

    Create a colorful diagram of the olfactory system, highlighting the olfactory epithelium, receptor cells, and olfactory tract. Use different colors to represent the journey of smell molecules from your nose to your brain. This visual activity will reinforce your understanding of how smells are processed.

  3. Smell and Memory Connection

    Think of a scent that brings back a strong memory for you. Write a short story or draw a picture about that memory and how the scent is connected to it. This activity will help you explore the link between smell and memory, as discussed in the article.

  4. Olfactory Trivia Game

    Create a trivia game with questions about the sense of smell. Include questions about the olfactory epithelium, receptor cells, and the differences in smell perception among people. Play the game with your classmates to test your knowledge and learn more about how we smell.

  5. Smell Sensitivity Test

    Conduct a simple experiment to test your sensitivity to different smells. Use diluted solutions of various scents and see how many you can identify at different concentrations. Record your results and compare them with your classmates to understand the variability in smell perception.

Here’s a sanitized version of the transcript:

It’s the first sense you use when you’re born. One out of every fifty of your genes is dedicated to it. It must be important, right? Okay, take a deep breath through your nose. It’s your sense of smell, and it’s incredibly powerful. As an adult, you can distinguish about 10,000 different smells. Here’s how your nose does it.

Smell starts when you inhale molecules from the air into your nostrils. Ninety-five percent of your nasal cavity is used just to filter that air before it reaches your lungs. But at the very back of your nose is a region called the olfactory epithelium, a small patch of tissue that is key to everything you smell. The olfactory epithelium contains a layer of olfactory receptor cells, special neurons that sense smells, similar to taste buds.

When odor molecules reach the back of your nose, they get trapped in a layer of mucus covering the olfactory epithelium. As they dissolve, they bind to the olfactory receptor cells, which then send signals through the olfactory tract to your brain. Interestingly, you can tell a lot about how good an animal’s sense of smell is by the size of its olfactory epithelium. For example, a dog’s olfactory epithelium is significantly larger than that of humans.

However, there is still much we don’t understand about this area. For instance, our olfactory epithelium is pigmented, and scientists are still investigating why. So how do you actually differentiate between smells? Your brain has around 40 million different olfactory receptor neurons, allowing for a vast array of combinations. For example, odor A might activate specific neurons, while odor B activates a different set. This diversity enables you to detect a wide range of smells.

Olfactory neurons are unique in that they are regularly replaced every four to eight weeks. Once activated, the signals travel through a bundle called the olfactory tract to various destinations in your brain, including the amygdala, thalamus, and neocortex. This process differs from how sight and sound are processed, as those signals first go to a relay center in the cerebral hemisphere before reaching other brain regions. Smell, having evolved earlier, takes a more direct route to these areas, influencing your emotional responses, memory recall, and even appetite.

Despite having the same physiological setup, not everyone perceives smells in the same way. A well-known example is the ability to detect a specific odor after consuming asparagus; about a quarter of the population can smell it, while the majority cannot. Additionally, some individuals perceive the chemical androstenone differently—some find it reminiscent of vanilla, while others detect a scent similar to sweat.

The inability to smell a scent is known as anosmia, with around 100 recognized types. For instance, some people cannot smell garlic or cloves, and others may experience complete anosmia due to various reasons, including congenital conditions, accidents, or illnesses. Swelling or infection of the olfactory epithelium can also impair smell, which many people experience when sick.

Not being able to smell can affect your other senses as well. Many individuals with anosmia also struggle to taste food as we typically do, since taste is closely linked to smell. When you chew, air carries the aroma of your food up to your nasal passage, where it interacts with the olfactory epithelium, providing essential information about what you’re eating. Without the ability to smell, you may only perceive the basic tastes: sweet, salty, bitter, sour, and savory.

So, the next time you encounter various scents, you’ll have a better understanding of how your sense of smell works and perhaps feel a bit more grateful for it.

This version maintains the informative content while removing any potentially sensitive or inappropriate language.

SmellThe ability to detect and identify odors through the nose. – The smell of flowers is detected by special cells in the nose that send signals to the brain.

MoleculesSmall particles made of atoms that form the basic units of chemical compounds. – Water molecules are made up of two hydrogen atoms and one oxygen atom.

OlfactoryRelating to the sense of smell. – The olfactory system includes the nose and the brain areas that process smells.

NeuronsNerve cells that transmit information throughout the body. – Neurons in the brain help process information from our senses.

BrainThe organ in the head that controls thoughts, memory, and other functions. – The brain interprets signals from the eyes to help us see.

ReceptorsSpecialized cells or proteins that detect specific stimuli like light, sound, or chemicals. – Taste receptors on the tongue help us identify different flavors.

AnosmiaThe loss or absence of the sense of smell. – People with anosmia may not be able to detect the aroma of freshly baked bread.

AromaA pleasant or distinctive smell. – The aroma of the coffee filled the room as it brewed.

SensesThe physiological capacities of organisms that provide data for perception. – Our senses include sight, hearing, taste, touch, and smell.

TissueA group of cells that work together to perform a specific function in the body. – Muscle tissue helps the body move by contracting and relaxing.

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